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Retinoid X Receptor alpha antibody (N-Term)

RXRA Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Cow WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782274
  • Target See all Retinoid X Receptor alpha (RXRA) Antibodies
    Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))
    Binding Specificity
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 58
    • 30
    • 26
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Dog, Cow
    Host
    • 46
    • 9
    • 3
    Rabbit
    Clonality
    • 40
    • 17
    Polyclonal
    Conjugate
    • 34
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Retinoid X Receptor alpha antibody is un-conjugated
    Application
    • 42
    • 27
    • 14
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    DTKHFLPLDF STQVNSSLTS PTGRGSMAAP SLHPSLGPGI GSPGQLHSPI
    Predicted Reactivity
    Cow: 80%, Dog: 87%, Guinea Pig: 87%, Human: 100%, Mouse: 87%, Rat: 87%
    Characteristics
    This is a rabbit polyclonal antibody against RXRA. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human RXRA
    Top Product
    Discover our top product RXRA Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 462 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))
    Alternative Name
    RXRA (RXRA Products)
    Synonyms
    NR2B1 antibody, 9530071D11Rik antibody, Nr2b1 antibody, RXRalpha1 antibody, RXRalpha antibody, rxra-A antibody, xRXR alpha antibody, xrxra antibody, RXRA antibody, RXR alpha antibody, etID309731.5 antibody, rxr antibody, rxra antibody, rxrg antibody, RXRalpha-B antibody, retinoid X receptor alpha antibody, retinoid X receptor alpha L homeolog antibody, retinoid x receptor, alpha b antibody, retinoid X receptor, alpha a antibody, RXRA antibody, Rxra antibody, rxra.L antibody, CpipJ_CPIJ010249 antibody, rxrab antibody, rxraa antibody
    Background
    Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. RXRA is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: FLJ16020, FLJ16733, MGC102720, NR2B1
    Protein Interaction Partner: PPARG, VDR, NCOA1, NSD1, UBC, NR1I3, NCOA4, THRB, THRA, ALOX15B, RARA, PPARA, CHD9, PRKD2, NR0B2, STAT1, NR3C2, SMAD2, GK, JAZF1, ACVR1B, NR1I2, NCOA2, PSMC5, RAD54L2, ARID5A, PML, SUMO1, ESR2, ESR1, BHLHE40, BHLHE41, NR4A1, EP300, NCOR1, NCOA6, NCOA3, TR
    Protein Size: 462
    Molecular Weight
    51 kDa
    Gene ID
    6256
    NCBI Accession
    NM_002957, NP_002948
    UniProt
    P19793
    Pathways
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C
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