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Liver Arginase antibody (N-Term)

ARG1 Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Pig, Horse, Goat, Guinea Pig, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782309
  • Target See all Liver Arginase (ARG1) Antibodies
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    Binding Specificity
    • 24
    • 20
    • 16
    • 12
    • 12
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Rat, Mouse, Rabbit, Cow, Dog, Pig, Horse, Goat, Guinea Pig, Saccharomyces cerevisiae
    Host
    • 110
    • 28
    • 5
    • 3
    • 2
    Rabbit
    Clonality
    • 107
    • 41
    Polyclonal
    Conjugate
    • 83
    • 13
    • 11
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Liver Arginase antibody is un-conjugated
    Application
    • 100
    • 59
    • 34
    • 30
    • 22
    • 20
    • 14
    • 14
    • 13
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    SAKSRTIGII GAPFSKGQPR GGVEEGPTVL RKAGLLEKLK EQECDVKDYG
    Cross-Reactivity
    Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%
    Characteristics
    This is a rabbit polyclonal antibody against ARG1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ARG1
    Top Product
    Discover our top product ARG1 Primary Antibody
  • Application Notes
    WB Suggested Anti-ARG1 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: Human Liver.
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 322 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kitowska, Zakrzewicz, Königshoff, Chrobak, Grimminger, Seeger, Bulau, Eickelberg: "Functional role and species-specific contribution of arginases in pulmonary fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 1, pp. L34-45, (2008) (PubMed).

  • Target
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    Alternative Name
    Arginase-1 (ARG1 Products)
    Synonyms
    SI:zC146F4.4 (novel protein with NUDIX domain) antibody, si:ch211-146f4.3 antibody, argi1 antibody, AI antibody, AI256583 antibody, Arg-1 antibody, PGIF antibody, arginase 1 antibody, arginase antibody, Arginase-1 antibody, arginase, liver antibody, L-arginase antibody, arg1 antibody, PGTG_16455 antibody, argi1 antibody, ARG1 antibody, Arg1 antibody
    Background
    Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: RPA3, RPA2, RPA1, SUZ12, EZH2, BMI1, ALDH4A1, ESR1, RAD21, UBC, UCHL5, ATG101, USP53, FLOT1, NOS1, ARG2,
    Protein Size: 322
    Molecular Weight
    35 kDa
    Gene ID
    383
    NCBI Accession
    NM_000045, NP_000036
    UniProt
    P05089
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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