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HAL antibody (N-Term)

HAL Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Cow, Dog, Guinea Pig, Horse, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782320
  • Target See all HAL Antibodies
    HAL (Histidine Ammonia-Lyase (HAL))
    Binding Specificity
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Cow, Dog, Guinea Pig, Horse, Pig
    Host
    • 15
    • 3
    Rabbit
    Clonality
    • 17
    • 1
    Polyclonal
    Conjugate
    • 14
    • 2
    • 1
    • 1
    This HAL antibody is un-conjugated
    Application
    • 13
    • 7
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    INKLQELQVN LVRSHSSGVG KPLSPERCRM LLALRINVLA KGYSGISLET
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against HAL. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human HAL
    Top Product
    Discover our top product HAL Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 657 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Alemán, Ortíz, Langley, Tovar, Torres: "Regulation by glucagon of the rat histidase gene promoter in cultured rat hepatocytes and human hepatoblastoma cells." in: American journal of physiology. Endocrinology and metabolism, Vol. 289, Issue 1, pp. E172-9, (2005) (PubMed).

  • Target
    HAL (Histidine Ammonia-Lyase (HAL))
    Alternative Name
    HAL (HAL Products)
    Synonyms
    HIS antibody, HSTD antibody, hal antibody, hstd antibody, xhal antibody, HAL antibody, BA3712 antibody, DDBDRAFT_0187742 antibody, DDBDRAFT_0231727 antibody, DDB_0187742 antibody, DDB_0231727 antibody, zgc:136980 antibody, his antibody, Hsd antibody, histidase antibody, histidine ammonia-lyase antibody, histidine ammonia-lyase, gene 1 L homeolog antibody, histidine ammonia-lyase HutH antibody, histidine ammonia-lyase, gene 1 antibody, histidine ammonia lyase antibody, HAL antibody, hal.1.L antibody, hutH antibody, Tc00.1047053506247.220 antibody, Plav_1493 antibody, hal antibody, hal.1 antibody, Hal antibody
    Background
    HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.
    Alias Symbols: HIS, HSTD, histidase
    Protein Interaction Partner: UBC,
    Protein Size: 657
    Molecular Weight
    72 kDa
    Gene ID
    3034
    NCBI Accession
    NM_002108, NP_002099
    UniProt
    P42357
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