CBR1 antibody (Middle Region)

Catalog No. ABIN2782364

Product Details anti-CBR1 Antibody

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AEVTMKTNFF GTRDVCTELL PLIKPQGRVV NVSSIMSVRA LKSCSPELQQ

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against CBR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CBR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 277 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CBR1 antibody (ABIN2782364)

Mitani, Ito, Harada, Nakano, Inui, Ashida, Yamaji: "Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells." in: Journal of nutritional science and vitaminology, Vol. 60, Issue 2, pp. 122-8, (2014) (PubMed).

Lim, Shin, Jo, Jyothi, Nguyen, Choi, Kim, Park, Eun, Yoon, Ha, Kim: "Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1784-93, (2013) (PubMed).

Target Details for CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Alternative Name: CBR1 (CBR1 Products)

Synonyms: LOC100222525 antibody, MGC131152 antibody, CBR antibody, SDR21C1 antibody, hCBR1 antibody, 9-KPR antibody, AW261796 antibody, CR antibody, Cbr antibody, carbonyl reductase 1 antibody, carbonyl reductase [NADPH] 1 antibody, carbonyl reductase 1 S homeolog antibody, carbonyl reductase antibody, cbr1 antibody, CBR1 antibody, LOC100222525 antibody, cbr1.S antibody, Smp_033530.3 antibody, LOC610164 antibody, Cbr1 antibody

Background: Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues.
Alias Symbols: CBR, hCBR1, SDR21C1
Protein Interaction Partner: MDM2, GRB2, VHL, ESR1, UBC, COPS5, CUL1, UL27, RAD21, Mapk13, UBA5, DDA1, ATG101, PRKAB1, EGFR, ERCC8, MCC,
Protein Size: 277

Molecular Weight: 30 kDa

Gene ID: 873

NCBI Accession: NM_001757, NP_001748

UniProt: P16152