MEMO1 antibody (Middle Region)
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- Target See all MEMO1 Antibodies
- MEMO1 (Mediator of Cell Motility 1 (MEMO1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MEMO1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- CHWGQRFRYS YYDESQGEIY RSIEHLDKMG MSIIEQLDPV SFSNYLKKYH
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against Memo1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product MEMO1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 297 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MEMO1 (Mediator of Cell Motility 1 (MEMO1))
- Alternative Name
- Memo1 (MEMO1 Products)
- Synonyms
- MGC89105 antibody, C2orf4 antibody, MEMO antibody, NS5ATP7 antibody, 0610016J10Rik antibody, D930048L02Rik antibody, RGD1309929 antibody, fi04d12 antibody, wu:fi04d12 antibody, zgc:55290 antibody, mediator of cell motility 1 antibody, mediator of cell motility 1 L homeolog antibody, MEMO1 antibody, memo1 antibody, Memo1 antibody, memo1.L antibody
- Background
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Memo1 may control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. It is a mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
Alias Symbols: 0610016J10Rik, D930048L02Rik
Protein Size: 297 - Molecular Weight
- 34 kDa
- Gene ID
- 76890
- NCBI Accession
- NM_133771, NP_598532
- UniProt
- Q91VH6
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