CRYZ antibody (Middle Region)

Catalog No. ABIN2782462

Product Details anti-CRYZ Antibody

Target: CRYZ (Crystallin, zeta (CRYZ))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Pig, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYZ antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KGIDIIIEML ANVNLSKDLS LLSHGGRVIV VGSRGTIEIN PRDTMAKESS

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 85%, Rat: 86%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CRYZ. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRYZ

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 329 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRYZ

Target: CRYZ (Crystallin, zeta (CRYZ))

Alternative Name: CRYZ (CRYZ Products)

Synonyms: CRYZ antibody, wu:fq09a05 antibody, zgc:110776 antibody, cryz antibody, MGC79715 antibody, Sez9 antibody, crystallin zeta antibody, crystallin, zeta (quinone reductase) antibody, crystallin zeta L homeolog antibody, zeta-crystallin antibody, crystallin, zeta antibody, CRYZ antibody, cryz antibody, cryz.L antibody, PTRG_02583 antibody, PTRG_07455 antibody, VDBG_03981 antibody, Cryz antibody

Background: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. CRYZ is a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low.Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. One pseudogene is known to exist.
Alias Symbols: DKFZp779E0834, FLJ41475
Protein Interaction Partner: UBC, TXNRD1, TUBA4A, SPTAN1, PFKP, KRT17, GAPDH, TUBB, IGF2BP3, BASP1, CRYAA,
Protein Size: 329

Molecular Weight: 35 kDa

Gene ID: 1429

NCBI Accession: NM_001889, NP_001880

UniProt: Q08257