MAGEA3 antibody (Middle Region)

Catalog No. ABIN2782498

Product Details anti-MAGEA3 Antibody

Target: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: APEEKIWEEL SVLEVFEGRE DSILGDPKKL LTQHFVQENY LEYRQVPGSD

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MAGEA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAGEA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 314 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAGEA3

Target: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Alternative Name: MAGEA3 (MAGEA3 Products)

Synonyms: CT1.3 antibody, HIP8 antibody, HYPD antibody, MAGE3 antibody, MAGEA6 antibody, Mage-a3 antibody, MAGEA3 antibody, MAGE family member A3 antibody, melanoma antigen, family A, 3 antibody, melanoma antigen family A, 3 antibody, MAGEA3 antibody, Magea3 antibody

Background: MAGEA3 is a member of the MAGEA family. The members of this family have 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HIP8, HYPD, MAGE3, MAGEA6, MGC14613, CT1.3
Protein Interaction Partner: DNM1L, TRIM28, UBC, HLA-DRB1, SUMO2, HTT,
Protein Size: 314

Molecular Weight: 35 kDa

Gene ID: 4102

NCBI Accession: NM_005362, NP_005353

UniProt: P43357