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PDK3 antibody (Middle Region)

PDK3 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio), Dog, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782500
  • Target See all PDK3 Antibodies
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Binding Specificity
    • 14
    • 10
    • 9
    • 9
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 37
    • 32
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio), Dog, Horse, Rabbit
    Host
    • 56
    • 3
    Rabbit
    Clonality
    • 56
    • 3
    Polyclonal
    Conjugate
    • 31
    • 7
    • 6
    • 5
    • 5
    • 5
    This PDK3 antibody is un-conjugated
    Application
    • 52
    • 41
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    IYLKALSSES FERLPVFNKS AWRHYKTTPE ADDWSNPSSE PRDASKYKAK
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against PDK3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PDK3
    Top Product
    Discover our top product PDK3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 406 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Alternative Name
    PDK3 (PDK3 Products)
    Synonyms
    pdk3 antibody, PDK3 antibody, 2610001M10Rik antibody, AI035637 antibody, zgc:158702 antibody, pyruvate dehydrogenase kinase 3 antibody, pyruvate dehydrogenase kinase, isozyme 3a antibody, pyruvate dehydrogenase kinase, isoenzyme 3 antibody, fragile site, 5-azacytidine type, common, fra(1)(q12) antibody, pyruvate dehydrogenase kinase, isozyme 3b antibody, PDK3 antibody, Pdk3 antibody, pdk3a antibody, pdk3 antibody, FRA1J antibody, pdk3b antibody
    Background
    PDK3 belongs to the PDK/BCKDK protein kinase family. It contains 1 histidine kinase domain. PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
    Alias Symbols: -
    Protein Interaction Partner: APP, UBD, UBC, ICT1, EGFR, DLAT, PDHA1,
    Protein Size: 406
    Molecular Weight
    47 kDa
    Gene ID
    5165
    NCBI Accession
    NM_005391, NP_005382
    UniProt
    Q15120
    Pathways
    PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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