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VARS antibody (Middle Region)

VARS Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782517
  • Target See all VARS Antibodies
    VARS (Valyl-tRNA Synthetase (VARS))
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 19
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae
    Host
    • 18
    • 2
    Rabbit
    Clonality
    • 19
    • 1
    Polyclonal
    Conjugate
    • 20
    This VARS antibody is un-conjugated
    Application
    • 19
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    VFDEFVDMDF GTGAVKITPA HDQNDYEVGQ RHGLEAISIM DSRGALINVP
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against VARS. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human VARS
    Top Product
    Discover our top product VARS Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1264 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Duarte, Videira: "Defective valyl-tRNA synthetase hampers the mitochondrial respiratory chain in Neurospora crassa." in: The Biochemical journal, Vol. 448, Issue 3, pp. 297-306, (2012) (PubMed).

    Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    VARS (Valyl-tRNA Synthetase (VARS))
    Alternative Name
    VARS (VARS Products)
    Synonyms
    G7A antibody, VARS1 antibody, VARS2 antibody, VARS antibody, Bat6 antibody, D17H6S56E antibody, G7a antibody, Vars2 antibody, vars1 antibody, vars2 antibody, CHUNP6879 antibody, im:7137378 antibody, wu:fb07a11 antibody, wu:fb07d10 antibody, TrsVal antibody, BEST:LD45671 antibody, CG4062 antibody, Dmel\\CG4062 antibody, VRS antibody, ValRS antibody, l(2)03531 antibody, l(2)rI255 antibody, ld45671 antibody, ECK4251 antibody, JW4215 antibody, val-act antibody, T5E21.11 antibody, T5E21_11 antibody, TWIN 2 antibody, VALRS antibody, VALYL TRNA SYNTHETASE antibody, valyl-tRNA synthetase antibody, Valyl-tRNA synthetase antibody, valyl-tRNA synthetase S homeolog antibody, hypothetical protein antibody, valyl-tRNA synthetase 2, mitochondrial antibody, valyl-tRNA synthetase / valine-tRNA ligase (VALRS) antibody, VARS antibody, Vars antibody, vars antibody, ValRS antibody, vars.S antibody, MW0078 antibody, Pnap_3169 antibody, valS antibody, Fnod_0343 antibody, Cyan7425_1070 antibody, Tola_0553 antibody, Slip_0680 antibody, Astex_3136 antibody, ML5_3395 antibody, VARS2 antibody, TWN2 antibody
    Background
    Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. VARS belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: G7A, VARS2, VARS1
    Protein Interaction Partner: CALCOCO2, SUMO2, SART3, STAU1, UBC, EED, CCT4, KNTC1, AIMP1, CCT3, QARS, EEF1G, EEF1D, EEF1B2, FBXO6, YWHAQ, MAPK11, VCAM1, ITGA4, FN1, LARS, CAD, UBD, SHC1, CUL3, CDK2, CHD7, CACNA1A, ATG101, OTUD5, DMWD, EEF1A1, EEF1A2, TRAF6, TFE3, HLA-B, EPB41,
    Protein Size: 1264
    Molecular Weight
    140 kDa
    Gene ID
    7407
    NCBI Accession
    NM_006295, NP_006286
    UniProt
    P26640
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