PIGQ antibody (N-Term)

Catalog No. ABIN2782620

Product Details anti-PIGQ Antibody

Target: PIGQ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Horse, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGQ antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PTVLPDRQAG ATTASTGGLA AVFDTVARSE VLFRSDRFDE GPVRLSHWQS

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PIGQ. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIGQ

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 581 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIGQ

Target: PIGQ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ))

Alternative Name: PIGQ (PIGQ Products)

Synonyms: GPI1 antibody, c407A10.1 antibody, Gpi1 antibody, Gpi1h antibody, Gpi1p antibody, Gpih antibody, phosphatidylinositol glycan anchor biosynthesis class Q antibody, phosphatidylinositol glycan anchor biosynthesis, class Q antibody, PIGQ antibody, Pigq antibody

Background: PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ is a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).
Alias Symbols: GPI1, MGC12693, c407A10.1, hGPI1
Protein Interaction Partner: SMAD1, UBC, PIGC, PIGH, PIGA, PIGP,
Protein Size: 581

Molecular Weight: 65 kDa

Gene ID: 9091

NCBI Accession: NM_004204, NP_004195

UniProt: Q9BRB3

Pathways: Inositol Metabolic Process