CHST2 antibody (Middle Region)

Catalog No. ABIN2782625

Product Details anti-CHST2 Antibody

Target: CHST2 (Carbohydrate (N-Acetylglucosamine-6-O) Sulfotransferase 2 (CHST2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VFQLYSPAGS GGRNLTTLGI FGAATNKVVC SSPLCPAYRK EVVGLVDDRV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Chst2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 530 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHST2

Target: CHST2 (Carbohydrate (N-Acetylglucosamine-6-O) Sulfotransferase 2 (CHST2))

Alternative Name: Chst2 (CHST2 Products)

Synonyms: chst2 antibody, wu:fj55f04 antibody, zgc:154070 antibody, CHST2 antibody, C6ST antibody, GST-2 antibody, GST2 antibody, Gn6ST-1 antibody, glcNAc6ST-1 antibody, AI428561 antibody, AW121776 antibody, C130041E03Rik antibody, Chts2 antibody, GlcNAc6ST antibody, Gn6st antibody, carbohydrate sulfotransferase 2 antibody, carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2a antibody, carbohydrate sulfotransferase 4 antibody, carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 antibody, carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 L homeolog antibody, CHST2 antibody, chst2a antibody, CHST4 antibody, chst2 antibody, chst2.L antibody, Chst2 antibody

Background: Chst2 catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as L-selectin ligands. L-selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Chst2 participates in biosynthesis of L-selectin ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. It has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. It sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.
Alias Symbols: AI428561, AW121776, C130041E03Rik, Chts2, GST-2, GlcNAc6ST, Gn6st
Protein Size: 530

Molecular Weight: 58 kDa

Gene ID: 54371

NCBI Accession: NM_018763, NP_061233

UniProt: Q80WV3

Pathways: Glycosaminoglycan Metabolic Process