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IL11RA antibody (N-Term)

IL11RA Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782643
  • Target See all IL11RA Antibodies
    IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
    Binding Specificity
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 27
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog
    Host
    • 28
    • 5
    Rabbit
    Clonality
    • 27
    • 5
    • 1
    Polyclonal
    Conjugate
    • 23
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL11RA antibody is un-conjugated
    Application
    • 23
    • 11
    • 10
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    QLGYPPARPV VSCQAADYEN FSCTWSPSQI SGLPTRYLTS YRKKTVLGAD
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against IL11RA. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human IL11RA
    Top Product
    Discover our top product IL11RA Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 422 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
    Alternative Name
    IL11RA (IL11RA Products)
    Synonyms
    CRSDA antibody, fi26e06 antibody, il-11ra antibody, wu:fi26e06 antibody, AI314697 antibody, GP130 antibody, Il-11ra antibody, Il11ra antibody, Il11ra2 antibody, NR1 antibody, interleukin 11 receptor subunit alpha antibody, interleukin 11 receptor, alpha antibody, interleukin 11 receptor subunit alpha 1 antibody, interleukin 11 receptor, alpha chain 1 antibody, IL11RA antibody, il11ra antibody, Il11ra1 antibody, Il11ra antibody
    Background
    Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. IL11RA is the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain.Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.
    Alias Symbols: MGC2146, CRSDA
    Protein Interaction Partner: IL11,
    Protein Size: 422
    Molecular Weight
    43 kDa
    Gene ID
    3590
    NCBI Accession
    NM_004512, NP_004503
    UniProt
    Q14626
    Pathways
    JAK-STAT Signaling, Growth Factor Binding
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