SSPN antibody (Middle Region)

Catalog No. ABIN2782663

Product Details anti-SSPN Antibody

Target: SSPN (Sarcospan (Kras Oncogene-Associated Gene) (SSPN))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Pig, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSPN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AHHYSQLTQF TCETTLDSCQ CKLPSSEPLS RTFVYRDVTD CTSVTGTFKL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SSPN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SSPN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 243 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SSPN

Target: SSPN (Sarcospan (Kras Oncogene-Associated Gene) (SSPN))

Alternative Name: SSPN (SSPN Products)

Synonyms: DAGA5 antibody, KRAG antibody, NSPN antibody, SPN1 antibody, SPN2 antibody, Krag antibody, RGD1559723 antibody, sarcospan S homeolog antibody, sarcospan antibody, sspn.S antibody, SSPN antibody, Sspn antibody

Background: SSPN is a member of the dystrophin-glycoprotein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells.SSPN gene is expressed in a variety of tissues with highest levels in muscle, where alternative splice variants have been observed. In certain tumors KRAS2, SSPN, and ITPR2 are coamplified. The function of this gene is unknown. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: KRAG, SPN1, SPN2, NSPN, DAGA5, nanospan
Protein Interaction Partner: Supt6, SGCG,
Protein Size: 243

Molecular Weight: 26 kDa

Gene ID: 8082

NCBI Accession: NM_005086, NP_005077

UniProt: Q14714