ATP2A3 antibody (Middle Region)
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- Target See all ATP2A3 Antibodies
- ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ATP2A3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LISGWLFFRY LAIGVYVGLA TVAAATWWFV YDAEGPHINF YQLRNFLKCS
- Predicted Reactivity
- Cow: 79%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Rabbit: 77%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against ATP2A3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ATP2A3
- Top Product
- Discover our top product ATP2A3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 999 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))
- Alternative Name
- ATP2A3 (ATP2A3 Products)
- Synonyms
- serca3 antibody, si:dkey-205l20.1 antibody, ATP2A3 antibody, Atp2a3 antibody, SERCA3 antibody, SERCA3b antibody, Serca3 antibody, SERCA antibody, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 L homeolog antibody, ATPase, Ca++ transporting, ubiquitous antibody, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 antibody, atp2a3.L antibody, atp2a3 antibody, ATP2A3 antibody, Atp2a3 antibody
- Background
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ATP2A3 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction.This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: SERCA3
Protein Interaction Partner: BCL2, UBC, BMI1, HDAC11, env, ATF2, CDK2, TCF3, IRS1, WRAP73,
Protein Size: 999 - Molecular Weight
- 109 kDa
- Gene ID
- 489
- NCBI Accession
- NM_005173, NP_005164
- UniProt
- Q93084
- Pathways
- Myometrial Relaxation and Contraction, Ribonucleoside Biosynthetic Process
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