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ATP2A3 antibody (Middle Region)

ATP2A3 Reactivity: Human, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782669
  • Target See all ATP2A3 Antibodies
    ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))
    Binding Specificity
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 23
    • 15
    • 15
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse
    Host
    • 23
    • 2
    Rabbit
    Clonality
    • 23
    • 2
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATP2A3 antibody is un-conjugated
    Application
    • 24
    • 13
    • 13
    • 9
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LISGWLFFRY LAIGVYVGLA TVAAATWWFV YDAEGPHINF YQLRNFLKCS
    Predicted Reactivity
    Cow: 79%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Rabbit: 77%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against ATP2A3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ATP2A3
    Top Product
    Discover our top product ATP2A3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 999 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))
    Alternative Name
    ATP2A3 (ATP2A3 Products)
    Synonyms
    serca3 antibody, si:dkey-205l20.1 antibody, ATP2A3 antibody, Atp2a3 antibody, SERCA3 antibody, SERCA3b antibody, Serca3 antibody, SERCA antibody, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 L homeolog antibody, ATPase, Ca++ transporting, ubiquitous antibody, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 antibody, atp2a3.L antibody, atp2a3 antibody, ATP2A3 antibody, Atp2a3 antibody
    Background
    ATP2A3 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction.This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: SERCA3
    Protein Interaction Partner: BCL2, UBC, BMI1, HDAC11, env, ATF2, CDK2, TCF3, IRS1, WRAP73,
    Protein Size: 999
    Molecular Weight
    109 kDa
    Gene ID
    489
    NCBI Accession
    NM_005173, NP_005164
    UniProt
    Q93084
    Pathways
    Myometrial Relaxation and Contraction, Ribonucleoside Biosynthetic Process
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