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LMAN1 antibody (N-Term)

LMAN1 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782680
  • Target See all LMAN1 Antibodies
    LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
    Binding Specificity
    • 15
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 45
    • 15
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Guinea Pig
    Host
    • 42
    • 2
    • 1
    Rabbit
    Clonality
    • 40
    • 5
    Polyclonal
    Conjugate
    • 20
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This LMAN1 antibody is un-conjugated
    Application
    • 33
    • 13
    • 13
    • 12
    • 8
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    DPAVALPHRR FEYKYSFKGP HLVQSDGTVP FWAHAGNAIP SSDQIRVAPS
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against LMAN1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human LMAN1
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    Discover our top product LMAN1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 510 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
    Alternative Name
    LMAN1 (LMAN1 Products)
    Synonyms
    ERGIC-53 antibody, ERGIC53 antibody, F5F8D antibody, FMFD1 antibody, MCFD1 antibody, MR60 antibody, gp58 antibody, 2610020P13Rik antibody, AI326273 antibody, AU043785 antibody, C730041J05 antibody, P58 antibody, p58 antibody, LMAN1 antibody, cpx-iii antibody, cpxiii antibody, lman1 antibody, wu:fc54c09 antibody, wu:fi36e01 antibody, Xp58 antibody, lman1-a antibody, lectin, mannose binding 1 antibody, lectin, mannose-binding, 1 antibody, complexin 3 antibody, lectin, mannose binding 1 S homeolog antibody, LMAN1 antibody, Lman1 antibody, cplx3 antibody, lman1 antibody, lman1.S antibody
    Background
    LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58
    Protein Interaction Partner: UBC, NEDD8, YIPF3, env, PIGS, TMED2, YBX1, HSP90AA1, HNRNPU, APP, UBXN6, RAB3GAP2, RAB3GAP1, COPE, TUBB4B, TUBB3, COPB2, VCP, DNAJC7, P4HB, HSPA8, HSPA1A, COPB1, COPA, BCAP29, BCAP31, HLA-A, CANX, ELAVL1, MCFD2, F8,
    Protein Size: 510
    Molecular Weight
    54 kDa
    Gene ID
    3998
    NCBI Accession
    NM_005570, NP_005561
    UniProt
    P49257
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