Corin antibody (C-Term)
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- Target See all Corin (CORIN) Antibodies
- Corin (CORIN) (Corin, Serine Peptidase (CORIN))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse, Cow, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Corin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MGNKMPFKLQ EGEVRIIPLE QCQSYFDMKT ITNRMICAGY ESGTVDSCMG
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Corin. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Corin
- Top Product
- Discover our top product CORIN Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1113 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Corin (CORIN) (Corin, Serine Peptidase (CORIN))
- Alternative Name
- Corin (CORIN Products)
- Synonyms
- CORIN antibody, CG2105 antibody, Dmel\\CG2105 antibody, SP75 antibody, LOC559109 antibody, AV273130 antibody, Lrp4 antibody, ATC2 antibody, CRN antibody, PEE5 antibody, TMPRSS10 antibody, corin, serine peptidase antibody, CG2105 gene product from transcript CG2105-RC antibody, novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN) antibody, corin antibody, CORIN antibody, Corin antibody, LOC559109 antibody
- Background
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Corin is a Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. It converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Corin also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide.
Alias Symbols: AV273130, Lrp4
Protein Size: 1113 - Molecular Weight
- 123 kDa
- Gene ID
- 53419
- NCBI Accession
- NM_016869, NP_058565
- UniProt
- Q9Z319
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
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