TRAM2 antibody (C-Term)

Catalog No. ABIN2782779

Product Details anti-TRAM2 Antibody

Target: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAM2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YWKEQSAKRR VSAVPRPPAK LLKREPGYHE NGVVKAENGT SSRTKKLKSP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Tram2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Tram2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRAM2

Target: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Alternative Name: Tram2 (TRAM2 Products)

Synonyms: C330003D03Rik antibody, wu:fb20c11 antibody, wu:fi23a12 antibody, zgc:111902 antibody, zgc:55869 antibody, zgc:76937 antibody, tram2 antibody, translocation associated membrane protein 2 antibody, tram-like protein antibody, TraM-like protein antibody, translocating chain-associating membrane protein 2 antibody, translocation associated membrane protein 2 L homeolog antibody, TRAM2 antibody, CJE0444 antibody, BT_p548215 antibody, traM antibody, CJJ81176_0418 antibody, Tram2 antibody, tram2 antibody, tram2.L antibody

Background: Tram2 is necessary for collagen type I synthesis. It may couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Alias Symbols: C330003D03Rik
Protein Size: 370

Molecular Weight: 40 kDa

Gene ID: 170829

NCBI Accession: NM_177409, NP_803128

UniProt: Q924Z5