TNFRSF21 antibody (N-Term)
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- Target See all TNFRSF21 Antibodies
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNFRSF21 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TTTAQPEQKA SNLIGTYRHV DRATGQVLTC DKCPAGTYVS EHCTNTSLRV
- Predicted Reactivity
- Cow: 92%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 91%, Rabbit: 93%, Rat: 91%
- Characteristics
- This is a rabbit polyclonal antibody against TNFRSF21. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF21
- Top Product
- Discover our top product TNFRSF21 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 655 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
- Alternative Name
- TNFRSF21 (TNFRSF21 Products)
- Synonyms
- TNFRSF21 antibody, tnfrsf21 antibody, MGC146356 antibody, BM-018 antibody, CD358 antibody, DR6 antibody, AA959878 antibody, R74815 antibody, TR7 antibody, dr6 antibody, im:6795346 antibody, wu:fa55e01 antibody, wu:fb02e11 antibody, wu:fc29a09 antibody, wu:fi27h08 antibody, TNF receptor superfamily member 21 antibody, tumor necrosis factor receptor superfamily member 21 antibody, tumor necrosis factor receptor superfamily, member 21 antibody, TNFRSF21 antibody, tnfrsf21 antibody, Tnfrsf21 antibody
- Background
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TNFRSF21 is a member of the TNF-receptor superfamily. This receptor has been shown to activate!!NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of!!TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
Alias Symbols: BM-018, DR6, MGC31965, CD358
Protein Interaction Partner: NSD1, CLIP3, ELAVL1, WASH2P, MATR3, STX11, TRADD,
Protein Size: 655 - Molecular Weight
- 68 kDa
- Gene ID
- 27242
- NCBI Accession
- NM_014452, NP_055267
- UniProt
- O75509
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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