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ERVW-1 antibody (N-Term)

ERVW-1 Reactivity: Human, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782821
  • Target See all ERVW-1 Antibodies
    ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))
    Binding Specificity
    • 8
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 38
    • 2
    • 1
    Human, Rabbit
    Host
    • 38
    Rabbit
    Clonality
    • 38
    Polyclonal
    Conjugate
    • 13
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERVW-1 antibody is un-conjugated
    Application
    • 26
    • 23
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    TQTGMSDGGG VQDQAREKHV KEVISQLTRV HGTSSPYKGL DLSKLHETLR
    Predicted Reactivity
    Human: 100%, Rabbit: 91%
    Characteristics
    This is a rabbit polyclonal antibody against ERVWE1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ERVWE1
    Top Product
    Discover our top product ERVW-1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 538 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ERVW-1 (Endogenous Retrovirus Group W, Member 1 (ERVW-1))
    Alternative Name
    ERVWE1 (ERVW-1 Products)
    Synonyms
    ENV antibody, ENVW antibody, ERVWE1 antibody, HERV-7q antibody, HERV-W-ENV antibody, HERV7Q antibody, HERVW antibody, HERVWENV antibody, endogenous retrovirus group W member 1, envelope antibody, ERVW-1 antibody
    Background
    ERVWE1 or syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The product of this gene, syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: Env-W, HERV-7q, HERV-W, HERV-W-ENV, HERVW, env, syncytin, ENV, ENVW, ERVWE1, HERV7Q, HERVWENV
    Protein Interaction Partner: SLC1A4, SLC1A5,
    Protein Size: 538
    Molecular Weight
    24 kDa
    Gene ID
    30816
    NCBI Accession
    NM_014590, NP_055405
    UniProt
    Q9UQF0
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