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CHST15 antibody (Middle Region)

CHST15 Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Cow, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782860
  • Target See all CHST15 Antibodies
    CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))
    Binding Specificity
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Rat, Mouse, Dog, Guinea Pig, Horse, Cow, Rabbit
    Host
    • 4
    • 1
    Rabbit
    Clonality
    • 4
    • 1
    Polyclonal
    Conjugate
    • 5
    This CHST15 antibody is un-conjugated
    Application
    • 5
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    YDNSTDGEPP FLTQDFIHAF QPNARLIVML RDPVERLYSD YLYFASSNKS
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against GALNAC4S-6ST. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human GALNAC4S-6ST
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 561 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))
    Alternative Name
    GALNAC4S-6ST (CHST15 Products)
    Synonyms
    GALNAC4S-6ST antibody, BRAG antibody, RP11-47G11.1 antibody, 4631426J05Rik antibody, GalNAcS-6ST antibody, MAd5 antibody, mKIAA0598 antibody, GalNAc4S6ST antibody, Galnac4s-6st antibody, carbohydrate sulfotransferase 15 antibody, carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 antibody, CHST15 antibody, chst15 antibody, Chst15 antibody
    Background
    GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression, however such results are unclear in vivo.
    Alias Symbols: BRAG, DKFZp781H1369, KIAA0598, MGC34346, RP11-47G11.1, GALNAC4S-6ST
    Protein Interaction Partner: UBC, RRAGD, LYN, HCK,
    Protein Size: 561
    Molecular Weight
    65 kDa
    Gene ID
    51363
    NCBI Accession
    NM_015892, NP_056976
    UniProt
    Q7LFX5
    Pathways
    Glycosaminoglycan Metabolic Process
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