C-Type Lectin Domain Family 1, Member B (CLEC1B) (N-Term) antibody

Catalog No. ABIN2782892

Product Details

Target: C-Type Lectin Domain Family 1, Member B (CLEC1B)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Sequence: MQDEDGYITL NIKPRKQALS SAEPASSWWR VMALVLLISS MGLVVGLVAL

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 85%, Rat: 93%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against Clec1b. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 229 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: C-Type Lectin Domain Family 1, Member B (CLEC1B)

Alternative Name: Clec1b (CLEC1B Products)

Synonyms: 1810061I13Rik antibody, CLEC2 antibody, CLEC2B antibody, PRO1384 antibody, QDED721 antibody, Clec-2 antibody, Clec2 antibody, CLEC1B antibody, RGD1563517 antibody, CLEC9A antibody, C-type lectin domain family 1 member B antibody, C-type lectin domain family 1, member b antibody, C-type lectin domain family 1, member B antibody, CLEC1B antibody, Clec1b antibody

Target Type: Viral Protein

Background: Clec1b acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2.
Alias Symbols: 1810061I13Rik, AI465458, Clec-2, Clec2, mCLEC-2
Protein Size: 229

Molecular Weight: 26 kDa

Gene ID: 56760

NCBI Accession: NM_019985, NP_064369

UniProt: Q9JL99