LPCAT2 antibody (C-Term)

Catalog No. ABIN2782921

Product Details anti-LPCAT2 Antibody

Target: LPCAT2 (Lysophosphatidylcholine Acyltransferase 2 (LPCAT2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Pig, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPCAT2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LGVPDLNVSG LFREIAQRDS VSYEEFKSFA LKHPEYAKIF TTYLDLQTCH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against Lpcat2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 544 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LPCAT2

Target: LPCAT2 (Lysophosphatidylcholine Acyltransferase 2 (LPCAT2))

Alternative Name: Lpcat2 (LPCAT2 Products)

Synonyms: AYTL1 antibody, LysoPAFAT antibody, A330042H22 antibody, Aytl1 antibody, Aytl1a antibody, lpafat1 antibody, aytl1 antibody, zgc:112165 antibody, LPCAT-2 antibody, RGD1563994 antibody, lysophosphatidylcholine acyltransferase 2 antibody, Lysophosphatidylcholine acyltransferase 2 antibody, LPCAT2 antibody, Lpcat2 antibody, lpcat2 antibody, pcat2 antibody

Background: Lpcat2 possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. It is involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). It also converts lyso-PAF to 1-alkyl-phosphatidylcholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases.
Alias Symbols: A330042H22, Aytl1, LPCAT2, lpafat1, Aytl1a
Protein Size: 544

Molecular Weight: 60 kDa

Gene ID: 270084

NCBI Accession: NM_173014, NP_766602

UniProt: Q8BYI6