FTO antibody (Middle Region)
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- Target See all FTO Antibodies
- FTO (Fat Mass and Obesity-Associated (FTO))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FTO antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- WWCQPMAQLE ALWKKMEGVT NAVLHEVKRE GLPVEQRNEI LTAILASLTA
- Predicted Reactivity
- Dog: 86%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against FTO. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FTO
- Top Product
- Discover our top product FTO Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 505 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FTO (Fat Mass and Obesity-Associated (FTO))
- Alternative Name
- FTO (FTO Products)
- Synonyms
- AW743446 antibody, mKIAA1752 antibody, RGD1305121 antibody, FTO, alpha-ketoglutarate dependent dioxygenase antibody, fat mass and obesity associated antibody, fat mass and obesity associated L homeolog antibody, FTO antibody, Fto antibody, fto.L antibody
- Background
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The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.
Alias Symbols: KIAA1752, MGC5149
Protein Interaction Partner: UBC, SUMO1, NEDD8, BCCIP, CNDP2, DAK, NDRG1, NPEPPS, SLC9A3R1, CTSA, PEPD, MVD, LDHB, LDHA, EEF2, CKB,
Protein Size: 505 - Molecular Weight
- 58 kDa
- Gene ID
- 79068
- NCBI Accession
- NM_001080432, NP_001073901
- UniProt
- Q9C0B1
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