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FTO antibody (Middle Region)

FTO Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782981
  • Target See all FTO Antibodies
    FTO (Fat Mass and Obesity-Associated (FTO))
    Binding Specificity
    • 18
    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 62
    • 27
    • 24
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig
    Host
    • 54
    • 8
    • 1
    • 1
    Rabbit
    Clonality
    • 44
    • 20
    Polyclonal
    Conjugate
    • 35
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FTO antibody is un-conjugated
    Application
    • 57
    • 23
    • 19
    • 14
    • 14
    • 13
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    WWCQPMAQLE ALWKKMEGVT NAVLHEVKRE GLPVEQRNEI LTAILASLTA
    Predicted Reactivity
    Dog: 86%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against FTO. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human FTO
    Top Product
    Discover our top product FTO Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 505 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FTO (Fat Mass and Obesity-Associated (FTO))
    Alternative Name
    FTO (FTO Products)
    Synonyms
    AW743446 antibody, mKIAA1752 antibody, RGD1305121 antibody, FTO, alpha-ketoglutarate dependent dioxygenase antibody, fat mass and obesity associated antibody, fat mass and obesity associated L homeolog antibody, FTO antibody, Fto antibody, fto.L antibody
    Background
    The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.
    Alias Symbols: KIAA1752, MGC5149
    Protein Interaction Partner: UBC, SUMO1, NEDD8, BCCIP, CNDP2, DAK, NDRG1, NPEPPS, SLC9A3R1, CTSA, PEPD, MVD, LDHB, LDHA, EEF2, CKB,
    Protein Size: 505
    Molecular Weight
    58 kDa
    Gene ID
    79068
    NCBI Accession
    NM_001080432, NP_001073901
    UniProt
    Q9C0B1
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