MAML3 antibody (Middle Region)

Catalog No. ABIN2783063

Product Details anti-MAML3 Antibody

Target: MAML3 (Mastermind-Like 3 (MAML3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rabbit, Horse, Cow, Rat, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAML3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YPVQQVNQFQ GSPQDIAAVR SQAALQSMRT SRLMAQNAGM MGIGPSQNPG

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MAML3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAML3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1133 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAML3

Target: MAML3 (Mastermind-Like 3 (MAML3))

Alternative Name: MAML3 (MAML3 Products)

Synonyms: AV234550 antibody, BC049812 antibody, Mam-2 antibody, mKIAA1816 antibody, Glrp1 antibody, CAGH3 antibody, ERDA3 antibody, GDN antibody, MAM-2 antibody, MAM2 antibody, TNRC3 antibody, mastermind like 3 (Drosophila) antibody, mastermind-like transcriptional coactivator 3 antibody, mastermind like transcriptional coactivator 3 antibody, Maml3 antibody, MAML3 antibody

Background: MAML3 acts as a transcriptional coactivator for NOTCH proteins. MAML3 has been shown to amplify NOTCH-induced transcription of HES1.
Alias Symbols: CAGH3, ERDA3, GDN, MAM-2, MAM2, TNRC3
Protein Interaction Partner: NOTCH1, ZZZ3, SCMH1, ZBTB1, RAI1, SUPT5H, NFX1, NOTCH3, NOTCH2, NOTCH4, MAML1, CSHL1,
Protein Size: 1133

Molecular Weight: 122 kDa

Gene ID: 55534

NCBI Accession: NM_018717, NP_061187

UniProt: Q96JK9