Nephronectin antibody (Middle Region)

Catalog No. ABIN2783147

Product Details anti-Nephronectin Antibody

Target: Nephronectin (NPNT)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Dog, Rat, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nephronectin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TTGLTTIAPA ASTPPGGITV DNRVQTDPQK PRGDVFIPRQ PSNDLFEIFE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NPNT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NPNT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 565 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Nephronectin

Target: Nephronectin (NPNT)

Alternative Name: NPNT (NPNT Products)

Synonyms: POEM antibody, si:ch211-202n8.2 antibody, egfl6l antibody, 1110009H02Rik antibody, AA682063 antibody, AI314031 antibody, Nctn antibody, EGFL6L antibody, nephronectin antibody, NPNT antibody, npnt antibody, Npnt antibody

Background: NPNT is a functional ligand of integrin alpha-8/beta-1 in kidney development. It regulates with integrin alpha-8/beta-1 the expression of GDNF which is essential for kidney development. It may also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins.
Alias Symbols: EGFL6L, POEM
Protein Interaction Partner: ITGA8,
Protein Size: 565

Molecular Weight: 62 kDa

Gene ID: 255743

NCBI Accession: NM_001033047, NP_001028219

UniProt: Q6UXI9