FBXO42 antibody (Middle Region)

Catalog No. ABIN2783173

Product Details anti-FBXO42 Antibody

Target: FBXO42 (F-Box Protein 42 (FBXO42))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO42 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RSMDEAPCVN GRWGTLRPRA QRQTPSGSRE GSLSPARGDG SPILNGGSLS

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO42. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO42

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 717 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO42

Target: FBXO42 (F-Box Protein 42 (FBXO42))

Alternative Name: FBXO42 (FBXO42 Products)

Synonyms: Fbx42 antibody, JFK antibody, 6720460I06Rik antibody, mKIAA1332 antibody, zgc:64224 antibody, wu:fj14e08 antibody, MGC84191 antibody, FBXO42 antibody, F-box protein 42 antibody, F-box protein 42 L homeolog antibody, FBXO42 antibody, Fbxo42 antibody, fbxo42 antibody, fbxo42.L antibody

Background: Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbx42, KIAA1332, JFK
Protein Interaction Partner: SMURF1, NEDD8, COPS6, CUL1, UBC, RBX1, TP53, SKP1,
Protein Size: 717

Molecular Weight: 78 kDa

Gene ID: 54455

NCBI Accession: NM_018994, NP_061867

UniProt: Q6P3S6