Peroxiredoxin 2 antibody (Middle Region)

Catalog No. ABIN2783315

Product Details anti-Peroxiredoxin 2 Antibody

Target: Peroxiredoxin 2 (PRDX2)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Goat, Horse, Sheep, Cow, Guinea Pig, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VLGVSVDSQF THLAWINTPR KEGGLGPLNI PLLADVTRRL SEDYGVLKTD

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Sheep: 100%, Yeast: 92%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against PRDX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRDX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 198 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Peroxiredoxin 2

Target: Peroxiredoxin 2 (PRDX2)

Alternative Name: PRDX2 (PRDX2 Products)

Background: PRDX2 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms.This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA, TPX1
Protein Interaction Partner: UBC, NEDD8, IPO11, CACYBP, PPP2R5D, PRDX1, METTL1, HECW2, ESR1, RAD52, NLGN3, CD320, COPS5, PRDX4, YWHAZ, VCAM1, UTY, SAT1, ITGA4, FN1, CA4, BAD, TPM3P4, TIPRL, TMEM9, RNF32, URM1, RIF1, EXOC6, CYCS, ECSIT, PRDX5, IFIT5, MAST1, PARK7, SEC23IP, CDC37, PRDX
Protein Size: 198

Molecular Weight: 22 kDa

Gene ID: 7001

NCBI Accession: NM_005809, NP_005800

UniProt: P35704