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UGP2 antibody (N-Term)

UGP2 Reactivity: Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783324
  • Target See all UGP2 Antibodies
    UGP2 (UDP-Glucose Pyrophosphorylase 2 (UGP2))
    Binding Specificity
    • 15
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 24
    • 19
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse
    Host
    • 39
    • 3
    Rabbit
    Clonality
    • 40
    • 2
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This UGP2 antibody is un-conjugated
    Application
    • 33
    • 13
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    TKKDLDGFRK LFHRFLQEKG PSVDWGKIQR PPEDSIQPYE KIKARGLPDN
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against UGP2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human UGP2
    Top Product
    Discover our top product UGP2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 497 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    UGP2 (UDP-Glucose Pyrophosphorylase 2 (UGP2))
    Alternative Name
    UGP2 (UGP2 Products)
    Synonyms
    DDBDRAFT_0204359 antibody, DDBDRAFT_0214911 antibody, DDB_0204359 antibody, DDB_0214911 antibody, UDPG antibody, UDPGP antibody, UDPGP2 antibody, UGP1 antibody, UGPP1 antibody, UGPP2 antibody, pHC379 antibody, Ugp2 antibody, fi53h10 antibody, wu:fi53h10 antibody, zgc:85662 antibody, AtUGP1 antibody, T17B22.6 antibody, T17B22_6 antibody, UDP-GLUCOSE PYROPHOSPHORYLASE 1 antibody, UDP-glucose pyrophosphorylase antibody, UGP antibody, UGPASE antibody, UGPase antibody, UDP-glucose pyrophosphorylase 2 antibody, UDP-glucose pyrophosphorylase 2 L homeolog antibody, UDP-glucose pyrophosphorylase 2b antibody, UDP-GLUCOSE PYROPHOSPHORYLASE 1 antibody, UDP-glucose pyrophosphorylase precursor antibody, ugpB antibody, ugp2.L antibody, UGP2 antibody, Ugp2 antibody, ugp2b antibody, LOAG_08596 antibody, DICPUDRAFT_55932 antibody, UGP1 antibody, LOC102577726 antibody
    Background
    UGP2 is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen, in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme.The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen, in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: UDPG, UDPGP2, UGPP2, pH C379
    Protein Interaction Partner: GLRX3, ARIH2, UGP2, UBC, NUSAP1, PUF60, PACSIN2, FAF1, PAPOLA, HSPH1, NUDC, CARM1, FARSB, USP15, RANBP3, HIRIP3, CUL1, CSDE1, ZYX, TARS, TROVE2, SET, PTPN12, PPP2R5C, PPM1G, PLOD2, CC2D1B, VASN, PARVA, ILK, GART, BUB1B, LYN, CBS, MROH2B, DNPEP, ISG15, ABC
    Protein Size: 497
    Molecular Weight
    56 kDa
    Gene ID
    7360
    NCBI Accession
    NM_001001521, NP_001001521
    Pathways
    Cellular Glucan Metabolic Process
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