TKT antibody (N-Term)

Catalog No. ABIN2783411

Product Details anti-TKT Antibody

Target: TKT (Transketolase (TKT))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TKT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: ESYHKPDQQK LQALKDTANR LRISSIQATT AAGSGHPTSC CSAAEIMAVL

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against TKT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TKT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 623 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TKT antibody (ABIN2783411)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for TKT

Target: TKT (Transketolase (TKT))

Alternative Name: TKT (TKT Products)

Synonyms: TK antibody, TKT1 antibody, p68 antibody, Dmel\\CG8036 antibody, anon-WO0118547.344 antibody, cb860 antibody, fb38f03 antibody, fj52f12 antibody, id:ibd3270 antibody, wu:cegs2794 antibody, wu:fb38f03 antibody, wu:fj52f12 antibody, tkt1 antibody, PSPTO0385 antibody, Tb08.11J15.550 antibody, xcc-b100_0966 antibody, transketolase antibody, CG8036 gene product from transcript CG8036-RB antibody, TransKeTolase homolog antibody, transketolase b antibody, transketolase L homeolog antibody, transketolase Tkt antibody, tkt antibody, TKT antibody, Tkt antibody, CG8036 antibody, tkt-1 antibody, tktb antibody, tkt.L antibody, tkt antibody, JK_RS05135 antibody, Tb927.8.6170 antibody, APH_RS01480 antibody

Background: TKT belongs to the transketolase family. TKT has been implicated in the latent genetic disease Wernicke-Korsakoff syndrome (WKS), which causes specific brain damage.
Alias Symbols: FLJ34765, TKT1, TK
Protein Interaction Partner: UBC, FUS, SUMO1, NEDD8, MDM2, FBXO6, SQSTM1, MYC, FN1, UFM1, UFC1, DYNC1LI1, AHCYL1, SSSCA1, VDAC3, UGDH, UBE2I, UBE2D1, TPI1, TALDO1, PKM, PRDX1, IGBP1, MYOC, CUL3, CDK2, ISG15, TERF1, AI837181, Csnk1e, HDAC5, H2AFX, PIK3C2A, ATG5, TKT,
Protein Size: 623

Molecular Weight: 68 kDa

Gene ID: 7086

NCBI Accession: NM_001064, NP_001055

UniProt: P29401