HMGCS1 antibody (Middle Region)

Catalog No. ABIN2783421

Product Details anti-HMGCS1 Antibody

Target: HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGCS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KDFTLNDFGF MIFHSPYCKL VQKSLARMLL NDFLNDQNRD KNSIYSGLEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HMGCS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HMGCS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 520 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMGCS1

Target: HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))

Alternative Name: HMGCS1 (HMGCS1 Products)

Synonyms: HMGCS antibody, zgc:56481 antibody, B130032C06Rik antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 1 antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 antibody, 3-hydroxy-3-methylglutaryl coenzyme A synthase antibody, hydroxymethylglutaryl-CoA synthase antibody, 3-hydroxy-3-methylglutaryl-CoA synthase antibody, hydroxymethylglutaryl coenzyme A synthase antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 1 S homeolog antibody, HMGCS1 antibody, hmgcs1 antibody, Hmgcs1 antibody, mvaS antibody, SAS2432 antibody, SZO_RS04705 antibody, SEQ_1109 antibody, NAEGRDRAFT_77778 antibody, hmgcs1.S antibody

Background: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Alias Symbols: HMGCS, MGC90332
Protein Interaction Partner: UBC, CLN5, SPDL1, SPG21, PEG10, MAPK9, PFN2, KARS, IARS, DARS,
Protein Size: 520

Molecular Weight: 57 kDa

Gene ID: 3157

NCBI Accession: NM_002130, NP_002121

UniProt: Q01581

Pathways: Regulation of Lipid Metabolism by PPARalpha