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CDY1 antibody (C-Term)

CDY1 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783449
  • Target See all CDY1 Antibodies
    CDY1 (Chromodomain Protein, Y-Linked, 1 (CDY1))
    Binding Specificity
    • 13
    • 7
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
    Host
    • 25
    Rabbit
    Clonality
    • 25
    Polyclonal
    Conjugate
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDY1 antibody is un-conjugated
    Application
    • 17
    • 14
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    FPRTWWQSAE DVHREKIQLD LEAEFYFTHL IVMFKSPRPA AMVLDRSQDF
    Predicted Reactivity
    Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 85%, Human: 100%, Mouse: 86%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against CDY1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CDY1
    Top Product
    Discover our top product CDY1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 554 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Stouffs, Tournaye, Van der Elst, Haentjens, Liebaers, Lissens: "Do we need to search for gr/gr deletions in infertile men in a clinical setting?" in: Human reproduction (Oxford, England), Vol. 23, Issue 5, pp. 1193-9, (2008) (PubMed).

  • Target
    CDY1 (Chromodomain Protein, Y-Linked, 1 (CDY1))
    Alternative Name
    CDY1 (CDY1 Products)
    Synonyms
    CDY antibody, CDY1A antibody, chromodomain Y-linked 1 antibody, CDY1 antibody
    Background
    CDY1 containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein.This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region, this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.
    Alias Symbols: CDY, CDY1A
    Protein Size: 554
    Molecular Weight
    62 kDa
    Gene ID
    9085
    NCBI Accession
    NM_004680, NP_004671
    UniProt
    A8K8F3
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