POLR1D antibody (Middle Region)

Catalog No. ABIN2783504

Product Details anti-POLR1D Antibody

Target: POLR1D (Polymerase (RNA) I Polypeptide D, 16kDa (POLR1D))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1D antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TRGTLPAVEP FQRGLNELMN VCQHVLDKFE ASIKDYKDQK ASRNESTF

Predicted Reactivity: Cow: 86%, Dog: 93%, Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against POLR1D. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human POLR1D

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 133 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POLR1D

Target: POLR1D (Polymerase (RNA) I Polypeptide D, 16kDa (POLR1D))

Alternative Name: POLR1D (POLR1D Products)

Background: POLR1D belongs to the archaeal rpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR1D is the common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs.
Alias Symbols: FLJ20616, MGC9850, POLR1C, RPA16, RPA9, RPAC2, RPO1-3, AC19, TCS2, RPC16
Protein Interaction Partner: POLR1C, UBC, DNAJB4, HAX1, DNAJB6, MRPL12, PXN, NR3C1, E2F4, DDIT3, CRKL, CDC25A, POLR3H, POLR1B, POLR3B, CRCP, POLR1A, POLR3A, POLR2C, POLR3D, GRB2, NFKBIB, MAGEA11, CD3EAP,
Protein Size: 133

Molecular Weight: 15 kDa

Gene ID: 51082

NCBI Accession: NM_015972, NP_057056

UniProt: Q9Y2S0