TGS1 antibody (Middle Region)

Catalog No. ABIN2783564

Product Details anti-TGS1 Antibody

Target: TGS1 (Trimethylguanosine Synthase 1 (TGS1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IDENPASDFD DSGSLLGFKY GSGQKYGGIP NFSHRQVRYL EKNVKLKSKY

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 93%, Horse: 85%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TGS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TGS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 853 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TGS1

Target: TGS1 (Trimethylguanosine Synthase 1 (TGS1))

Alternative Name: TGS1 (TGS1 Products)

Synonyms: NCOA6IP antibody, PIMT antibody, PIPMT antibody, D4Ertd800e antibody, Ncoa6ip antibody, Pimt antibody, trimethylguanosine synthase 1 antibody, trimethylguanosine synthase 1 L homeolog antibody, TGS1 antibody, Tgs1 antibody, tgs1.L antibody

Background: TGS1 catalyzes the methylation step(s) for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. TGS1 plays a role in transcriptional regulation.
Alias Symbols: DKFZp762A163, FLJ22995, NCOA6IP, PIMT, PIPMT
Protein Interaction Partner: LIN28A, UBC, COIL, Nhp2l1, NCOA6, HNF4A, EP300, EED, CREBBP, SNORD3A, MED1,
Protein Size: 853

Molecular Weight: 96 kDa

Gene ID: 96764

NCBI Accession: NM_024831, NP_079107

UniProt: Q96RS0

Pathways: Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization