CHSY3 antibody (N-Term)

Catalog No. ABIN2783650

Product Details anti-CHSY3 Antibody

Target: CHSY3 (Chondroitin Sulfate Synthase 3 (CHSY3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHSY3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PPLQQRRRGR EPEGATGLPG APAAEGEPEE EDGGAAGQRR DGRPGSSHNG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against CHSY-2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHSY-2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 882 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHSY3

Target: CHSY3 (Chondroitin Sulfate Synthase 3 (CHSY3))

Alternative Name: CHSY-2 (CHSY3 Products)

Background: CHSY-2 has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. CHSY-2 transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity of CHSY-2 is much reduced compared to CHSY1.CSS3 is a glycosyltransferase that has both glucuronyltransferase and N-acetylgalactosaminyltransferase activities (Yada et al., 2003 [PubMed 12907687]).[supplied by OMIM].
Alias Symbols: CHSY2, CSS3, CHSY-2
Protein Size: 882

Molecular Weight: 100 kDa

Gene ID: 337876

NCBI Accession: NM_175856, NP_787052

UniProt: Q70JA7

Pathways: Glycosaminoglycan Metabolic Process