UGT2B4 antibody (N-Term)

Catalog No. ABIN2783820

Product Details anti-UGT2B4 Antibody

Target: UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT2B4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: NIKTILDELV QRGHEVTVLA SSASISFDPN SPSTLKFEVY PVSLTKTEFE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against UGT2B4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UGT2B4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 528 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UGT2B4

Target: UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

Alternative Name: UGT2B4 (UGT2B4 Products)

Synonyms: HLUG25 antibody, UDPGTH1 antibody, UGT2B11 antibody, UDPGT2B4 antibody, UGT2B17 antibody, UGT2B28 antibody, UDP glucuronosyltransferase family 2 member B4 antibody, UDP-glucuronosyltransferase 2B4 antibody, UGT2B4 antibody, LOC615303 antibody, LOC100066359 antibody

Background: UGT2B4 belongs to the UDP-glycosyltransferase family. UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
Alias Symbols: UGT2B11, HLUG25, UDPGTH1, UDPGT2B4
Protein Interaction Partner: STAT5A,
Protein Size: 528

Molecular Weight: 60 kDa

Gene ID: 7363

NCBI Accession: NM_021139, NP_066962

UniProt: P06133

Pathways: Steroid Hormone Biosynthesis