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ZP4 antibody (N-Term)

ZP4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783828
  • Target See all ZP4 Antibodies
    ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))
    Binding Specificity
    • 8
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 33
    • 3
    • 3
    • 1
    Human
    Host
    • 33
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZP4 antibody is un-conjugated
    Application
    • 23
    • 20
    • 15
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MWLLRCVLLC VSLSLAVSGQ HKPEAPDYSS VLHCGPWSFQ FAVNLNQEAT
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ZP4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ZP4
    Top Product
    Discover our top product ZP4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 540 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))
    Alternative Name
    ZP4 (ZP4 Products)
    Synonyms
    ZPB antibody, xlZPB antibody, lzpb-a antibody, MGC154827 antibody, zbp antibody, zp1 antibody, ZBP antibody, TAC4 antibody, MGC154888 antibody, ZP1 antibody, Zp-4 antibody, ZP3-ALPHA antibody, ZP antibody, Zp-X antibody, zona pellucida glycoprotein 4 S homeolog antibody, zona pellucida glycoprotein 4 antibody, zona pellucida glycoprotein 4 L homeolog antibody, zp4.S antibody, zp4 antibody, ZP4 antibody, zp4.L antibody, Zp4 antibody
    Background
    The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ZBP, ZP1, ZPB, Zp-4
    Protein Interaction Partner: FURIN,
    Protein Size: 540
    Molecular Weight
    49 kDa
    Gene ID
    57829
    NCBI Accession
    NM_021186, NP_067009
    UniProt
    Q12836
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