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CYP3A4 antibody (C-Term)

CYP3A4 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep, Goat, Horse, Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783886
  • Target See all CYP3A4 Antibodies
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    Binding Specificity
    • 16
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 88
    • 37
    • 35
    • 17
    • 15
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep, Goat, Horse, Pig
    Host
    • 78
    • 9
    • 1
    Rabbit
    Clonality
    • 73
    • 15
    Polyclonal
    Conjugate
    • 49
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CYP3A4 antibody is un-conjugated
    Application
    • 71
    • 24
    • 21
    • 20
    • 18
    • 16
    • 13
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    IYALHHDPKY WTEPEKFCPE SRFSKKNKDS IDLYRYIPFG AGPRNCIGMR
    Predicted Reactivity
    Cow: 92%, Dog: 86%, Goat: 85%, Guinea Pig: 80%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 85%, Rat: 92%, Sheep: 92%
    Characteristics
    This is a rabbit polyclonal antibody against CYP3A43. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CYP3A43
    Top Product
    Discover our top product CYP3A4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 504 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    Alternative Name
    CYP3A43 (CYP3A4 Products)
    Synonyms
    CP33 antibody, CP34 antibody, CYP3A antibody, CYP3A3 antibody, CYPIIIA3 antibody, CYPIIIA4 antibody, HLP antibody, NF-25 antibody, P450C3 antibody, P450PCN1 antibody, MGC108372 antibody, CYP3A80 antibody, CYP3A4 antibody, CYP3A21 antibody, CYPIIIA21 antibody, CYP3A12 antibody, cytochrome P450 family 3 subfamily A member 4 antibody, cytochrome P450 family 3 subfamily A member 43 antibody, cytochrome P450 3A4 antibody, cytochrome P450, subfamily IIIA, polypeptide 4 antibody, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody, cytochrome P450, family 3, subfamily A, polypeptide 4 antibody, CYP3A4 antibody, CYP3A43 antibody, PTRG_01782 antibody, PTRG_06060 antibody, cyp3a4 antibody
    Background
    CYP3A43 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.
    Alias Symbols: MGC119315, MGC119316
    Protein Size: 504
    Molecular Weight
    58 kDa
    Gene ID
    64816
    NCBI Accession
    NM_022820, NP_073731
    UniProt
    Q9HB55
    Pathways
    Steroid Hormone Biosynthesis
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