CYP2R1 antibody (Middle Region)
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- Target See all CYP2R1 Antibodies
- CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Pig, Dog, Horse, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP2R1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- FKQLITNAVS NITNLIIFGE RFTYEDTDFQ HMIELFSENV ELAASASVFL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against CYP2R1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CYP2R1
- Top Product
- Discover our top product CYP2R1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 501 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))
- Alternative Name
- CYP2R1 (CYP2R1 Products)
- Synonyms
- cytochrome P450 family 2 subfamily R member 1 antibody, cytochrome P450, family 2, subfamily R, polypeptide 1 antibody, cytochrome P450, family 2, subfamily r, polypeptide 1 antibody, CYP2R1 antibody, cyp2r1 antibody, Cyp2r1 antibody
- Background
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.
Alias Symbols: MGC4663
Protein Size: 501 - Molecular Weight
- 57 kDa
- Gene ID
- 120227
- NCBI Accession
- NM_024514, NP_078790
- UniProt
- Q6VVX0
- Pathways
- Metabolism of Steroid Hormones and Vitamin D
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