CYP2R1 antibody (C-Term)

Catalog No. ABIN2783925

Product Details anti-CYP2R1 Antibody

Target: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2R1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ALVPFSLGRR HCLGEHLARM EMFLFFTALL QRFHLHFPHE LVPDLKPRLG

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 85%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CYP2R1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYP2R1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CYP2R1

Target: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Alternative Name: CYP2R1 (CYP2R1 Products)

Synonyms: cytochrome P450 family 2 subfamily R member 1 antibody, cytochrome P450, family 2, subfamily R, polypeptide 1 antibody, cytochrome P450, family 2, subfamily r, polypeptide 1 antibody, CYP2R1 antibody, cyp2r1 antibody, Cyp2r1 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.
Alias Symbols: CYP2R1
Protein Size: 501

Molecular Weight: 55 kDa

Gene ID: 120227

NCBI Accession: NM_024514, NP_078790

UniProt: Q6VVX0

Pathways: Metabolism of Steroid Hormones and Vitamin D