SRD5A3 antibody (N-Term)

Catalog No. ABIN2783928

Product Details anti-SRD5A3 Antibody

Target: SRD5A3 (Steroid 5 alpha-Reductase 3 (SRD5A3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRD5A3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GLLPGCAIFQ DLIRYGKTKC GEPSRPAACR AFDVPKRYFS HFYIISVLWN

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 89%

Characteristics: This is a rabbit polyclonal antibody against SRD5A3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SRD5A3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 318 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SRD5A3 antibody (ABIN2783928)

Uemura, Tamura, Chung, Honma, Okuyama, Nakamura, Nakagawa: "Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer." in: Cancer science, Vol. 99, Issue 1, pp. 81-6, (2007) (PubMed).

Target Details for SRD5A3

Target: SRD5A3 (Steroid 5 alpha-Reductase 3 (SRD5A3))

Alternative Name: SRD5A3 (SRD5A3 Products)

Synonyms: CDG1P antibody, CDG1Q antibody, KRIZI antibody, SRD5A2L antibody, SRD5A2L1 antibody, 1110025P14Rik antibody, A430076C09 antibody, AV364670 antibody, AW987574 antibody, D730040M03Rik antibody, H5ar antibody, S5AR 3 antibody, Srd5a2l antibody, RGD1308828 antibody, SRD5alpha3 antibody, steroid 5 alpha-reductase 3 antibody, steroid 5 alpha-reductase 3 S homeolog antibody, SRD5A3 antibody, Srd5a3 antibody, srd5a3.S antibody

Background: SRD5A3 belongs to the steroid 5-alpha reductase family and converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
Alias Symbols: FLJ13352, SRD5A2L, CDG1P, CDG1Q, KRIZI, SRD5A2L1
Protein Interaction Partner: NUDT15, ADK, DFG10,
Protein Size: 318

Molecular Weight: 36 kDa

Gene ID: 79644

NCBI Accession: NM_024592, NP_078868

UniProt: Q9H8P0

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis