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H13 antibody (Middle Region)

H13 Reactivity: Human, Mouse, Rabbit, Dog, Guinea Pig, Horse, Rat, Cow, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783988
  • Target See all H13 Antibodies
    H13 (Histocompatibility 13 (H13))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    Middle Region
    Reactivity
    • 40
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rabbit, Dog, Guinea Pig, Horse, Rat, Cow, Zebrafish (Danio rerio)
    Host
    • 40
    Rabbit
    Clonality
    • 40
    Polyclonal
    Conjugate
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This H13 antibody is un-conjugated
    Application
    • 36
    • 22
    • 13
    • 13
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    IKLVFPQDLL EKGLEADNFA MLGLGDIVIP GIFIALLLRF DISLKKNTHT
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 92%
    Characteristics
    This is a rabbit polyclonal antibody against H13. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide corresponding to a region of Mouse
    Top Product
    Discover our top product H13 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 378 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    H13 (Histocompatibility 13 (H13))
    Alternative Name
    H13 (H13 Products)
    Synonyms
    H13 antibody, IMP1 antibody, IMPAS antibody, IMPAS-1 antibody, MSTP086 antibody, PSENL3 antibody, PSL3 antibody, SPP antibody, SPPL1 antibody, dJ324O17.1 antibody, cb228 antibody, zgc:56660 antibody, zgc:86862 antibody, wu:fc11a06 antibody, h13 antibody, MGC68919 antibody, 1200006O09Rik antibody, 4930443L17Rik antibody, 5031424B04Rik antibody, AV020344 antibody, H-13 antibody, Hm13 antibody, Spp antibody, histocompatibility minor 13 antibody, histocompatibility (minor) 13 antibody, histocompatibility (minor) 13 L homeolog antibody, histocompatibility 13 antibody, HM13 antibody, hm13 antibody, hm13.L antibody, H13 antibody, Hm13 antibody
    Background
    H13 catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. It is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. Involved in the intramembrane cleavage of the integral membrane protein PSEN1 By similarity. It may play a role in graft rejection.
    Alias Symbols: 1200006O09Rik, 4930443L17Rik, 5031424B04Rik, AV020344, H-13, Hm13, PSL3, Spp
    Protein Size: 378
    Molecular Weight
    42 kDa
    Gene ID
    14950
    NCBI Accession
    NM_010376, NP_034506
    UniProt
    Q9D8V0
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