ESYT3 antibody (Middle Region)

Catalog No. ABIN2784016

Product Details anti-ESYT3 Antibody

Target: ESYT3 (Extended Synaptotagmin-Like Protein 3 (ESYT3))

Binding Specificity: Middle Region

Reactivity: Rat, Human, Mouse, Guinea Pig, Dog, Rabbit, Cow, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESYT3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EVFEFMVYEV PGQDLEVDLY DEDTDRDDFL GSLQICLGDV MTNRVVDEWF

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against FAM62C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FAM62C

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 886 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ESYT3 antibody (ABIN2784016)

Craxton: "Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans." in: BMC genomics, Vol. 8, pp. 259, (2007) (PubMed).

Target Details for ESYT3

Target: ESYT3 (Extended Synaptotagmin-Like Protein 3 (ESYT3))

Alternative Name: FAM62C (ESYT3 Products)

Synonyms: Fam62c antibody, RGD1561304 antibody, fam62a antibody, fam62c antibody, FAM62A antibody, im:7153182 antibody, si:ch211-219a4.7 antibody, FAM62C antibody, DKFZp459I013 antibody, CHR3SYT antibody, E-Syt3 antibody, D930024E11 antibody, D9Ertd280e antibody, mKIAA4186 antibody, extended synaptotagmin 3 antibody, extended synaptotagmin protein 3 antibody, extended synaptotagmin-like protein 3 antibody, extended synaptotagmin-3 antibody, Esyt3 antibody, ESYT3 antibody, esyt3 antibody, LOC100468549 antibody, LOC100594943 antibody

Background: FAM62C belongs to the extended synaptotagmin family. It is a single-pass membrane protein, and contains 3 C2 domains. FAM62C may play a role as calcium-regulated intrinsic membrane protein.
Alias Symbols: CHR3SYT, E-Syt3, FAM62C
Protein Size: 886

Molecular Weight: 100 kDa

Gene ID: 83850

NCBI Accession: NM_031913, NP_114119

UniProt: A0FGR9