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TMEM123 antibody (C-Term)

TMEM123 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784103
  • Target See all TMEM123 Antibodies
    TMEM123 (Transmembrane Protein 123 (TMEM123))
    Binding Specificity
    • 16
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 30
    • 22
    • 21
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 27
    • 3
    Rabbit
    Clonality
    • 28
    • 2
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMEM123 antibody is un-conjugated
    Application
    • 29
    • 18
    • 13
    • 13
    • 6
    • 5
    • 3
    • 2
    Western Blotting (WB)
    Sequence
    SSVTITTTMH SEAKKGSKFD TGSFVGGIVL TLGVLSILYI GCKMYYSRRG
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against TMEM123. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human TMEM123
    Top Product
    Discover our top product TMEM123 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 208 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TMEM123 (Transmembrane Protein 123 (TMEM123))
    Alternative Name
    TMEM123 (TMEM123 Products)
    Synonyms
    KCT3 antibody, PORIMIN antibody, PORMIN antibody, 2310075C12Rik antibody, RGD1305625 antibody, kct3 antibody, pormin antibody, porimin antibody, transmembrane protein 123 antibody, transmembrane protein 123 L homeolog antibody, TMEM123 antibody, Tmem123 antibody, tmem123.L antibody, tmem123 antibody
    Background
    TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
    Alias Symbols: KCT3, PORIMIN, PORMIN
    Protein Interaction Partner: MAGEA11, ELAVL1,
    Protein Size: 208
    Molecular Weight
    19 kDa
    Gene ID
    114908
    NCBI Accession
    NM_052932, NP_443164
    UniProt
    Q8N131
    Pathways
    Regulation of Cell Size
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