ANKH antibody (N-Term)

Catalog No. ABIN2784109

Product Details anti-ANKH Antibody

Target: ANKH (Ankylosis, Progressive Homolog (Mouse) (ANKH))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Cow, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKH antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SDLGYYIINK LHHVDESVGS KTRRAFLYLA AFPFMDAMAW THAGILLKHK

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ANKH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANKH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 492 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ANKH

Target: ANKH (Ankylosis, Progressive Homolog (Mouse) (ANKH))

Alternative Name: ANKH (ANKH Products)

Synonyms: ANK antibody, CCAL2 antibody, CMDJ antibody, CPPDD antibody, HANK antibody, MANK antibody, Ank antibody, Ankh antibody, D15Ertd221e antibody, ank antibody, mKIAA1581 antibody, ankh antibody, wu:fc08d03 antibody, wu:fj64g09 antibody, zgc:110290 antibody, ANKH inorganic pyrophosphate transport regulator antibody, progressive ankylosis antibody, ANKH inorganic pyrophosphate transport regulator b antibody, ANKH inorganic pyrophosphate transport regulator S homeolog antibody, ANKH inorganic pyrophosphate transport regulator a antibody, ANKH antibody, Ankh antibody, Ank antibody, ankhb antibody, ankh.S antibody, ankha antibody

Background: ANKH regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ANK, CCAL2, CMDJ, CPPDD, FLJ27166, HANK, MANK
Protein Interaction Partner: UBC, RPSA, APOE,
Protein Size: 492

Molecular Weight: 54 kDa

Gene ID: 56172

NCBI Accession: NM_054027, NP_473368

UniProt: Q9HCJ1