UNC5A antibody (Middle Region)

Catalog No. ABIN2784134

Product Details anti-UNC5A Antibody

Target: UNC5A (Unc-5 Homolog A (UNC5A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC5A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VYCRKKEGLD SDVADSSILT SGFQPVSIKP SKADNPHLLT IQPDLSTTTT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against UNC5A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UNC5A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 842 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UNC5A

Target: UNC5A (Unc-5 Homolog A (UNC5A))

Alternative Name: UNC5A (UNC5A Products)

Synonyms: zgc:175190 antibody, UNC5H1 antibody, Unc5h1 antibody, mKIAA1976 antibody, unc-5 netrin receptor A antibody, netrin receptor UNC5A antibody, UNC5A antibody, Tsp_02512 antibody, Tsp_13881 antibody, unc5a antibody, Unc5a antibody

Background: UNC5A belongs to a family of netrin-1 receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C.UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C (MIM 603610).[supplied by OMIM].
Alias Symbols: FLJ16449, KIAA1976, UNC5H1
Protein Interaction Partner: DAP, MAGED1, NTN1, DAPK1,
Protein Size: 842

Molecular Weight: 93 kDa

Gene ID: 90249

NCBI Accession: NM_133369, NP_588610

UniProt: Q6ZN44