PHF6 antibody (C-Term)

Catalog No. ABIN2784475

Product Details anti-PHF6 Antibody

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DFDIKTVLQE IKRGKRMVCS FYICYATLHL ICCFKFRVHP KFIQSSENLK

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PHF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PHF6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 312 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHF6

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Alternative Name: PHF6 (PHF6 Products)

Synonyms: zgc:55403 antibody, wu:fa22g03 antibody, BFLS antibody, BORJ antibody, CENP-31 antibody, 2700007B13Rik antibody, 4931428F02Rik antibody, mKIAA1823 antibody, PHD finger protein 6 antibody, PHD finger protein 6 L homeolog antibody, phf6 antibody, phf6.L antibody, PHF6 antibody, Phf6 antibody

Background: PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. PHF6 is a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of its gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS).This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: BORJ, MGC14797, BFLS, CENP-31
Protein Interaction Partner: UBC, SUMO1, NEDD8, BMI1, HECW2, CAND1, CUL3, HDGF,
Protein Size: 312

Molecular Weight: 35 kDa

Gene ID: 84295

NCBI Accession: NM_032335, NP_115711

UniProt: Q5JRC7