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PHF6 antibody (N-Term)

PHF6 Reactivity: Human, Mouse, Dog, Cow, Rat, Horse, Rabbit, Pig, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784476
  • Target See all PHF6 Antibodies
    PHF6 (PHD Finger Protein 6 (PHF6))
    Binding Specificity
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 32
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Dog, Cow, Rat, Horse, Rabbit, Pig, Guinea Pig
    Host
    • 30
    • 2
    Rabbit
    Clonality
    • 31
    • 1
    Polyclonal
    Conjugate
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHF6 antibody is un-conjugated
    Application
    • 20
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    VGQNHSEDGA PALLTTAPPP GLQPGAGGTP GGPGGGGAPP RYATLEHPFH
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PHF6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PHF6
    Top Product
    Discover our top product PHF6 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 365 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PHF6 (PHD Finger Protein 6 (PHF6))
    Alternative Name
    PHF6 (PHF6 Products)
    Synonyms
    zgc:55403 antibody, wu:fa22g03 antibody, BFLS antibody, BORJ antibody, CENP-31 antibody, 2700007B13Rik antibody, 4931428F02Rik antibody, mKIAA1823 antibody, PHD finger protein 6 antibody, PHD finger protein 6 L homeolog antibody, phf6 antibody, phf6.L antibody, PHF6 antibody, Phf6 antibody
    Background
    PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. PHF6 is a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation that localizes to the nucleolus. Mutations affecting the coding region of its gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears.This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: BORJ, MGC14797, BFLS, CENP-31
    Protein Interaction Partner: UBC, SUMO1, NEDD8, BMI1, HECW2, CAND1, CUL3, HDGF,
    Protein Size: 365
    Molecular Weight
    41 kDa
    Gene ID
    84295
    NCBI Accession
    NM_032458, NP_115834
    UniProt
    Q8IWS0
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