TAF3 antibody (Middle Region)

Catalog No. ABIN2784481

Product Details anti-TAF3 Antibody

Target: TAF3 (TAF3 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 140kDa (TAF3))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Dog, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RDREREKDKN KDKSKEKDKV KEKEKDKETG RETKYPWKEF LKEEEADPYK

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 92%, Human: 100%, Rabbit: 92%, Rat: 92%, Yeast: 79%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against TAF3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TAF3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 929 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAF3

Target: TAF3 (TAF3 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 140kDa (TAF3))

Alternative Name: TAF3 (TAF3 Products)

Background: Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF3 is required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.
Alias Symbols: MGC25063, TAF140, TAFII140, TAFII-140
Protein Interaction Partner: NPM1, MED26, HIST2H4A, HIST3H3, TAF10, KPNA2, KPNB1, TAF6, TAF5, TAF4, TAF1, CTCF, TBP, SAP130, TAF13, TAF12, TAF7, KAT2A, TBPL2, KHDRBS2,
Protein Size: 929

Molecular Weight: 103 kDa

Gene ID: 83860

NCBI Accession: NM_031923, NP_114129

UniProt: Q5VWG9

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process, Maintenance of Protein Location