HMGN3 antibody (Middle Region)

Catalog No. ABIN2784552

Product Details anti-HMGN3 Antibody

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGN3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QEPTRRSARL SAKPAPPKPE PKPRKTSAKK EPGAKISRGA KGKKEEKQEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HMGN3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human HMGN3

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMGN3

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Alternative Name: HMGN3 (HMGN3 Products)

Synonyms: Trip7 antibody, PNAS-25 antibody, TRIP7 antibody, 1110002A15Rik antibody, 6330514M13Rik antibody, BB071015 antibody, high mobility group nucleosomal binding domain 3 L homeolog antibody, high mobility group nucleosomal binding domain 3 antibody, hmgn3.L antibody, HMGN3 antibody, Hmgn3 antibody

Background: Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: UBC, SRPK2, SRPK1, TERF2, TERF1, TERF2IP, VDR, THRB,
Protein Size: 99

Molecular Weight: 10 kDa

Gene ID: 9324

UniProt: Q15651