Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DCK antibody (Middle Region)

DCK Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Horse, Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2784622
  • Target See all DCK Antibodies
    DCK (Deoxycytidine Kinase (DCK))
    Binding Specificity
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 51
    • 26
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Dog, Cow, Guinea Pig, Horse, Pig, Zebrafish (Danio rerio)
    Host
    • 43
    • 8
    • 3
    Rabbit
    Clonality
    • 48
    • 6
    Polyclonal
    Conjugate
    • 31
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCK antibody is un-conjugated
    Application
    • 39
    • 25
    • 25
    • 25
    • 22
    • 11
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ATPETCLHRI YLRGRNEEQG IPLEYLEKLH YKHESWLLHR TLKTNFDYLQ
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against DCK. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human DCK
    Top Product
    Discover our top product DCK Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 260 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bieghs, Caers, De Bruyne, Van Valckenborgh, Higginbotham, Vanderkerken, Menu: "The effects of forodesine in murine and human multiple myeloma cells." in: Advances in hematology, Vol. 2010, pp. 131895, (2010) (PubMed).

  • Target
    DCK (Deoxycytidine Kinase (DCK))
    Alternative Name
    DCK (DCK Products)
    Synonyms
    dck antibody, DCK antibody, wu:fc15f06 antibody, zgc:101771 antibody, dck1 antibody, deoxycytidine kinase antibody, deoxycytidine kinase, gene 2 L homeolog antibody, deoxycytidine kinase, gene 2 antibody, Deoxycytidine kinase antibody, deoxycytidine kinase, gene 1 L homeolog antibody, DCK antibody, dck antibody, dck.2.L antibody, dck.2 antibody, Dck antibody, FPV059 antibody, FPV151 antibody, dck.1.L antibody
    Background
    Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC117410, MGC138632
    Protein Interaction Partner: UBC, EFHD2, CHRAC1, CHMP4A, CBX3, TYMS, THOP1, TALDO1, RBBP7, RANBP1, PTMS, IDH1, HSPE1, ADSS, TFEC, ELAVL1, RXRG, DCK, MED19, GOLM1, DDX19B,
    Protein Size: 260
    Molecular Weight
    30 kDa
    Gene ID
    1633
    NCBI Accession
    NM_000788, NP_000779
    UniProt
    P27707
You are here:
Support